This presentation is focused on educating engineers about the wetted loop for liquid cooling in EV systems and the imperative for chemical compatibility of all components. Engineers will learn how to identify and and mitigate risks associated with material compatibility issues. While the examples for this presentation are framed for EV charging or battery swap system design engineers, the information on component specification, material selection, chemical compatibility and incompatibility consequences is relevant for all engineers designing liquid cooling systems regardless of application or market.